this post was submitted on 18 Jul 2025
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xkcd #3117: Replication Crisis

Title text:

Maybe encouraging the publication of null results isn't enough--maybe we need a journal devoted to publishing results the study authors find personally annoying.

Transcript:

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Source: https://xkcd.com/3117/

explainxkcd for #3117

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[–] [email protected] 109 points 1 day ago (1 children)

I once experienced this firsthand. The postdoc kept coming by, trying to find out how we were messing up something he had written a paper on. Eventually, he tried to reproduce it himself. No one could reproduce it, not even him.

[–] [email protected] 5 points 15 hours ago (2 children)

I'm guessing he still didn't admit his work might be wrong at that point?

[–] [email protected] 16 points 7 hours ago (1 children)

I would propose a more generous starting position than "you're wrong." Maybe "our understanding is incomplete."

There are many stories that could be a long the vein of one I saw personally: a night-shift leaning researcher can't get a protocol to work after being trained on it. They go back to the post-doc that trained them to troubleshoot - works flawlessly. When they do it by themselves (typically at night) it fails again.

After much agony and self-blame, turns out the enzyme they were studying was regulated by the organism's circadian cycle. They protein they were studying was off at night and no one knew.

Contradiction in science frequently masks a deeper biological truth.

[–] [email protected] 3 points 37 minutes ago

That's a charitable way of looking at it. A lot of big egos in academia is my first hand experience, so that's what I jump to.

[–] [email protected] 1 points 7 hours ago

If he did his career could be in jeopardy. It's not an honesty or integrity problem.