this post was submitted on 03 Aug 2023
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[–] [email protected] 9 points 2 years ago (21 children)

Looks like a treatment, not a cure, that will require ongoing supplies of medication. This is a pharma wet dream. We can’t cure your cancer, but we can keep it from growing for just $2000 per pill that cost us $1 to make.

[–] [email protected] 16 points 2 years ago* (last edited 2 years ago) (2 children)

Do you really think that pill cost 1$? A single approved therapy takes years to develop and over a billion dollars. But hey if you're view of an entire industry is shaped through Facebook comments I don't blame you.

Further, maintenance therapy already exists in many cancers. This is not a new concept for literally anyone in the field of medicine.

[–] [email protected] 24 points 2 years ago (3 children)

You speak like someone whose never had to buy insulin before.

[–] [email protected] 19 points 2 years ago (1 children)

Which is cheap or free in literally everywhere except the country of free. It’s US problem, not industry.

[–] [email protected] 5 points 2 years ago (2 children)

I'm from a country in western Europe, and our pharmacies are running low. My dad was told several times over the last months that they're out of stock and he should come back next week. Sure, the price here might be okay, but Pharma seems to prefer selling it more expensively elsewhere.

[–] [email protected] 4 points 2 years ago

They're probably creating artificial scarcity to increase the prices elsewhere on account of "supply and demand". There's a special place in hell for them.

[–] [email protected] 4 points 2 years ago

I live in the US, my wife couldn't find test strips for over a week.

[–] [email protected] 3 points 2 years ago (1 children)

You are doing exactly the thing the person you are replying to is calling someone out for, so if anything you are underlining the point. Pharmaceuticals is a vast industry, and the matter they work with is not homogenous.

You cannot infer from the cost of insulin to inhabitants of uncivilized western countries what the actual cost of providing a still in-development medicine will be. More specifically, you cannot expand from being ripped off in one country for one medicine and the myopic view that provides to pharmaceuticals as a whole.

As a counterpoint in your case, I pay nothing for my insulin, as its included the base medical insurance everyone has to have. As are a vast amount of other pharmaceuticals.

[–] [email protected] 3 points 2 years ago (1 children)

I gave an example of a treatment style pharmaceutical that has been used consistently to boost corporate profits rather than serve the greater good. Would you like to talk about the cost of epipens next? How about the opioid industry?

[–] [email protected] 4 points 2 years ago

A pill that treats solid tumours would be an enormous boon to humanity. You're letting really tired cynicism get in the way of basic logic. This argument would mean that insulin wasn't a breakthrough, because it didn't cure diabetes.

For profit pharmaceuticals is indeed a huge issue, but it's one that is entirely separate from whether or not a given medical treatment is good or not.

[–] [email protected] 1 points 2 years ago (1 children)

Insulin is worse though because it’s not like it’s a drug that had to be developed and has a billion dollars or more to develop. The case with insulin is blatant price gouging.

This pill, this doesn’t mean it should be as cheap as insulin as the two drugs aren’t equals. It can be priced fairly and still be expensive, we don’t know the economics behind it. Being cheap =/= fair pricing all the time. Like buying a better product that took more to make.

This could still be outrageously priced obviously, but comparing it to insulin is apples to oranges.

[–] [email protected] 0 points 2 years ago (1 children)

it doesn't look very advanced or hard to make honestly https://en.wikipedia.org/wiki/AOH1996

[–] [email protected] 2 points 2 years ago (1 children)

What is the indicator in the article that the compound is trivial to produce?

[–] [email protected] 2 points 2 years ago (2 children)

its structure, it's like 4 steps from widely available building blocks, all routine things (amide couplings, one palladium coupling or SNAr)

source: me, i'm an organic chemist

[–] [email protected] 2 points 2 years ago

depending on how you count, even less than 4 steps all starting materials are commercially available and probably pretty cheap

i'm not gonna talk down a molecule that's easy to make, but there may be room for modifications, should it be discovered that these are beneficial. this may or may not make synthesis a little bit harder or more expensive but at any rate not impossible

[–] [email protected] 11 points 2 years ago (1 children)

No I don’t think it will cost a dollar. That was hyperbole.

[–] [email protected] 0 points 2 years ago* (last edited 2 years ago)

That's what it is, a subscription based cure.

"as long as you buy our medicine you will live!"

I sure hope it isn't like this. Medicine just enough to stave the progress of the illness but also not enough to cure it.

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