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Nature is a weekly international journal publishing the finest peer-reviewed research in all fields of science and technology on the basis of its originality, importance, interdisciplinary interest, timeliness, accessibility, elegance and surprising conclusions. Nature also provides rapid, authoritative, insightful and arresting news and interpretation of topical and coming trends affecting science, scientists and the wider public.

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Nature, Published online: 23 April 2025; doi:10.1038/s41586-025-08975-3

Author Correction: Global influence of soil texture on ecosystem water limitation


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Nature, Published online: 23 April 2025; doi:10.1038/s41586-025-09029-4

Whole-body physics simulation of fruit fly locomotion


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Nature, Published online: 23 April 2025; doi:10.1038/s41586-025-09022-x

Publisher Correction: Oncolytic virus VG161 in refractory hepatocellular carcinoma


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Nature, Published online: 23 April 2025; doi:10.1038/s41586-025-09025-8

Geographic and age variations in mutational processes in colorectal cancer


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Nature, Published online: 23 April 2025; doi:10.1038/d41586-025-01284-9

Bendy, twisty and collapsable origami towers could make temperature controlling panels, or, dancing robots.


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Nature, Published online: 23 April 2025; doi:10.1038/d41586-025-01268-9

Tecovirimat, which has been approved to treat mpox, was no better than a placebo in a large trial.


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Nature, Published online: 23 April 2025; doi:10.1038/d41586-025-01271-0

Two studies show the extent of gunshot wounds inflicted by police and link certain police-department policies with a lower death toll.


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Nature, Published online: 23 April 2025; doi:10.1038/d41586-025-01283-w

Phoenician civilization thrived across the Mediterranean for more than 1,000 years.


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Nature, Published online: 23 April 2025; doi:10.1038/d41586-025-01288-5

We round up some recent stories from the Nature Briefing.


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Nature, Published online: 23 April 2025; doi:10.1038/d41586-025-01154-4

China takes pole position in cancer-related research in the Nature Index, with a massive jump in output.


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Nature, Published online: 23 April 2025; doi:10.1038/s41586-025-08880-9

Inflammatory monocytes in the brain meninges promote stress-induced fear behaviour, and the pathways involved can be modulated using psychedelic compounds.


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Nature, Published online: 23 April 2025; doi:10.1038/s41586-025-08895-2

Characterizing the superconducting gap structure in the high-temperature superconductor H3S by means of tunnelling spectroscopy reveals that it, as well as D3S, has a fully gapped structure, confirming the phonon-mediated mechanism of superconducting pairing.


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Nature, Published online: 23 April 2025; doi:10.1038/s41586-025-08751-3

A transparent and reproducible scientific framework is introduced to formalize how trillions in economic losses are attributable to the extreme heat caused by emissions from fossil fuel companies, which could inform climate liability claims.


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Nature, Published online: 23 April 2025; doi:10.1038/s41586-025-08919-x

Using high-throughput functional profiling, how disordered regions control mRNA stability and translation is explored.


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Nature, Published online: 23 April 2025; doi:10.1038/s41586-025-08902-6

Cold-sensitive engrams contribute to learned thermoregulation in mice that are returned to an environment in which they previously experienced a cold challenge, through a network formed between the hippocampus and hypothalamus that enables the recall of cold-related memories.


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Nature, Published online: 23 April 2025; doi:10.1038/s41586-025-08874-7

Atomic precision lift-off of ultrathin membranes without artificial release layers can be achieved to facilitate the high-throughput production of scalable, ultrathin, single-crystalline, freestanding perovskite systems.


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Nature, Published online: 23 April 2025; doi:10.1038/s41586-025-08846-x

Realistic-lithosphere numerical models suggest glacial forcing in the last glacial cycle notably affected plate motions and mid-ocean-ridge spreading rates near major ice sheets, with implications for modern polar deglaciation enhancing magmatism and markedly impacting climate.


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Nature, Published online: 23 April 2025; doi:10.1038/s41586-025-08801-w

A twin-field quantum key distribution protocol based on optical coherence is deployed over a 254-kilometre commercial telecom network, demonstrating that coherence-based quantum communication can be aligned with existing telecommunication infrastructure.


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Nature, Published online: 23 April 2025; doi:10.1038/s41586-025-08898-z

The core circadian transcription factor BMAL1 regulates circadian-dependent myocardial injury.


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Nature, Published online: 23 April 2025; doi:10.1038/s41586-025-08881-8

Generalization of a quantum twisting microscope to cryogenic temperatures in twisted bilayer graphene shows the ability to map phononic dispersions through inelastic momentum-conserving tunnelling and reveals an angle-dependent coupling between electrons and phonons.


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Nature, Published online: 23 April 2025; doi:10.1038/s41586-025-08938-8

ADP-heptose binds to ALPK1, triggering transcriptional reprogramming and NF-κB activation, endowing pre-leukaemic cells with a competitive advantage due to excessive clonal proliferation.


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Nature, Published online: 23 April 2025; doi:10.1038/s41586-025-08851-0

A versatile origami-inspired modular chiral mechanical metamaterial structure facilitates dual-mode actuation, converting compression into rotational motion and torsion into extension or compression.


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Nature, Published online: 23 April 2025; doi:10.1038/s41586-025-08865-8

3D seismic reflection images of the lithosphere–asthenosphere boundary beneath Axial volcano show a magma assimilation front that focuses magmatism towards the centre of the volcano, controlling both eruption and hydrothermal processes.


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Nature, Published online: 23 April 2025; doi:10.1038/s41586-025-08917-z

A study of human and mouse models of pancreatic cancer finds that inhibiting the lipid kinase PIKfyve interferes with the cancer’s lipid homeostasis, making it a potential target for drug development.


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Nature, Published online: 23 April 2025; doi:10.1038/s41586-025-08891-6

Characterization of the genetic architecture underlying the 7 pairs of contrasting traits studied by Mendel and the over 70 additional agronomic traits in pea (Pisum sativum) reveals their molecular details and provides tools for further studies in pea genetics, functional genomics and crop improvement.


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