Programming

I would definitely be concerned about the performance in this case, unless you can do some kind of AoT compilation of the scripts being executed (at least in production builds, development builds probably can't do that if you need hot reloading). Unfortunately the execution time budget is really tight if you want to get frequent updates and decent frame times (although if the system in question runs parallel to the rest of your systems, for example, then it might have more time to operate with).

That being said, with the interpreter pre-compiling those scripts, performance could still be really good. Sharing memory would become less relevant since your scripts would now operate on more than whatever's in your component storages and could now, in theory, work with variables local to the system, assuming you're meaning that the interpreter is called ad-hoc basically and isn't the entirety of the system.

This is all in theory of course, in practice you'd need to find an interpreter that supports pre-compiling (or at least pre-optimizing in some form) all the scripts you'll want to run if you want to maximize performance.