this post was submitted on 18 Apr 2024
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Science

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General discussions about "science" itself

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[–] [email protected] 67 points 1 year ago

Super interesting! I'm going to file this under "hope it's true, will wait for testing/confirmation because the claims are amazing".

[–] [email protected] 18 points 1 year ago (1 children)

Extraordinary claims require extraordinary proof.

As it is, the first time this was posted, biologists and pharmacists discussed the merits of the claims and came to the conclusion that this was unlikely to be real.

Specifically the approach would probably be thwarted the second time you attempted to use this method because your immune system would attack the vaccine.

The discussion also pointed out that this was why the second dose of Astrazeneca during the COVID pandemic was less effective.

Disclaimer: I'm not a medical professional and don't pretend to be one online. I'm reciting from memory. YMMV.

[–] [email protected] 36 points 1 year ago* (last edited 1 year ago) (1 children)

Extraordinary claims require extraordinary proof.

As it is, the first time this was posted, biologists and pharmacists discussed the merits of the claims and came to the conclusion that this was unlikely to be real.

Link please? Kinda feel like I shouldn't have had to ask for that based on how you chose to begin your comment but here we are.

[–] [email protected] 4 points 1 year ago (2 children)
[–] [email protected] 11 points 1 year ago (2 children)

So the "biologists and pharmacologists" you are citing are just armchair scientists in the Lemmy comment section

[–] [email protected] 5 points 1 year ago

On Hexbear, no less.

[–] [email protected] 3 points 1 year ago* (last edited 1 year ago)

Unaccountable armchair 'scientists' on hexbear no less. Lol.

Also once you finally get to someone discussing the content of the paper the entire tone about plausibility changes.

[–] [email protected] 7 points 1 year ago
[–] [email protected] 12 points 1 year ago (3 children)

Note that some studies show nine mouse days are roughly equivalent to one human year.

Excuse me?

[–] [email protected] 15 points 1 year ago

Basically mice procrastinate much less than people.

[–] [email protected] 7 points 1 year ago (1 children)

Given the position of this statement in the article, I'm guessing they are trying to imply a correlation in rate of aging. Like 1 dog year = 7 human years. They are further implying that if a mouse maintains immunity for 90 days, a human would maintain immunity for 10 years.

It should be clear that it is the reporter stating this, not the original authors of the study.

[–] [email protected] 4 points 1 year ago (3 children)

I'm no cell biologist but I don't think immunity works that way. I don't know enough to dispute it though.

[–] [email protected] 7 points 1 year ago (1 children)

I am a molecular biologist, and it kinda works this way. B cells are called memory cells because they hold onto that "memory" of the invader for a really long time. You probably haven't had an MMR or a Tetanus vaccine in 10+ years because the body is really good at remembering. But we have to get flu boosters every year because the flu mutates so rapidly that traditional b cells won't recognize the flu after a year of mutating. (RNA viruses can't correct their mutations so they change much faster than bacteria or DNA viruses). RNAi was still pretty new when I was in school and I haven't kept up with the research so I can't speak to it's effectiveness at long term immunity.

[–] [email protected] 4 points 1 year ago (1 children)

I know enough about that, the part I was skeptical about though was the assumption that if a mouse is immune for 90 days, a human would be immune for 10 years.

[–] [email protected] 3 points 1 year ago

And you are absolutely right to be skeptical about that, that is a crazy level of extrapolation.

[–] [email protected] 1 points 1 year ago

It is good that you recognize that you don't know enough to dispute it. Now just recognize that people who do know enough aren't disputing it.

[–] [email protected] 1 points 1 year ago

I assumed it had to do with heartbeats. Mice hearts beat much faster than human hearts, and I think of the heartbeat like a computer’s clock or an engine’s RPM. If you increase that, the rate of everything else increases.

[–] [email protected] 6 points 1 year ago

You're excused

[–] [email protected] 5 points 1 year ago (1 children)

I thought the thumbnail was a Smurf hand holding a crackpipe... I think I need to get more sleep.

[–] [email protected] 2 points 1 year ago

Or possibly less crack.

[–] [email protected] 4 points 1 year ago (1 children)

So I can stop drinking bleach?

[–] [email protected] 3 points 1 year ago (1 children)

No more light bulbs up the arse either.

[–] [email protected] 3 points 1 year ago (1 children)

Aww man, there go my weekend plans.

[–] [email protected] 2 points 1 year ago

Well, you can still do it if you enjoy it.

[–] [email protected] 2 points 1 year ago (6 children)

I don't vaccinate, and that is enough to get downvoted. :)

[–] [email protected] 33 points 1 year ago (1 children)
[–] [email protected] 24 points 1 year ago

Too bad that dumbass was vaccinated as an infant

[–] [email protected] 17 points 1 year ago

Don't procreate.

[–] [email protected] 15 points 1 year ago (1 children)

Luckily for you, there's not a vaccine for stupidity.

[–] [email protected] 1 points 1 year ago

Yes there is, it's just also made of toxic chemicals and increasing in price lately.

[–] [email protected] 15 points 1 year ago

So what do you know that literally all the scientists in the world don't?

[–] [email protected] 9 points 1 year ago

You're getting down voted because your post doesn't meaningfully contribute.

[–] [email protected] 6 points 1 year ago

Obvious troll is obvious.