Technology

With GPU passthrough you can get almost native performance. This requires 2 GPUs though (iGPU as second one should suffice), dunno about the input lag and stability though as I only have one GPU

Without it though? Not even worth trying

Proton is a better option unless the game needs Anti-Cheat, which most won't work in a VM, anyway

Personally I dual boot Win10 LTSC with fake credentials and some privacy tweaks for games that need to be on windows

I only play games that work native or via proton. I just use windows for the CAD programs that i need to use. I do gpu pass through and native for my host system idk how this would be for gaming tho.