336
This is fucking awesome.
this post was submitted on 20 Mar 2025
336 points (100.0% liked)
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The mechanism of this treatment is incredible. Basically destroying your marrow and replacing it with a genetically repaired version.
Marrow transplants aren't new, but the genetic modification of stem cells to create new marrow is massive. This could have wide-ranging treatment implications for a variety of diseases. Cancer, auto-immune disease, transplant rejection, and practically any blood-borne viral disease.
Oh wow, so we're finally getting there with genetically modifying and replicating internal organs in medicine?
That is, indeed, amazing news
Not modifying organs, but if you can modify the immune system by editing marrow genes, you could eliminate sensitivities to foreign MHC antigens.
I look forward to all funding for this disappearing given the target demographic.
All funding is diverted to the research of sickle cell anemia in white people. The leftover funding will go directly into the bank account of Elmo.
I am Jacks complete lack of sickle cell anemia
Unexpected [redacted] reference
Dude.
Fucking shush
How could I forget the first two rules
That Island man is long
I know someone with sickle cell, and it's really horrific. It would be amazing if a cure was widely available. I'm the current atmosphere, it's hard to imagine that happening, at least in the US, since it's POC who suffer.
Yeah ... it's great that this research was conducted and this result achieved before the current Executive Office came to power. They're doing everything they can to starve the systems (and the people) that produce results like this.
in New York history.
Also in general history ...
There are previous cases of sickle cell being cured by a bone transplant. The first was in 1983. Although in that case it seems like curing her sickle cell wasn’t the goal - she was being treated for cancer.
The first sickle cell patient treated with CRISPR was in about 2020.