| Tuesday | October 24 |  |
||
|---|---|---|---|---|
| New Mexico State | defeated | Louisiana Tech | 27-24 | Away |
| ^22^ Liberty | defeated | Western Kentucky | 42-29 | Away |
| Wednesday | October 25 | |
||
|---|---|---|---|---|
| Jacksonville State | defeated | Florida International | 41-16 | Away |
| UTEP | defeated | Sam Houston State | 37-34 | Away |
| Thursday | October 26 | |
||
|---|---|---|---|---|
| Virginia Tech | defeated | Syracuse | 38-10 | Home |
| Georgia Southern | defeated | Georgia State | 44-27 | Home |
| Friday | October 27 | |
||
|---|---|---|---|---|
| Florida Atlantic | defeated | Charlotte | 38-16 | Away |
| Saturday | October 28 | |
||
|---|---|---|---|---|
| UMass | defeated | Army | 21-14 | Away |
| West Virginia | defeated | UCF | 41-28 | Away |
| Northwestern | defeated | Maryland | 33-27 | Home |
| ^10^ Penn State | defeated | Indiana | 33-24 | Home |
| Texas A&M | defeated | South Carolina | 30-17 | Home |
| Kansas State | defeated | Houston | 41-0 | Home |
| ^4^ Florida State | defeated | Wake Forest | 41-16 | Away |
| Boston College | defeated | Connecticut | 21-14 | Home |
| SMU | defeated | Tulsa | 69-10 | Home |
| Kansas | defeated | ^3^ Oklahoma |
38-33 | Home |
| Western Michigan | defeated | Eastern Michigan | 45-21 | Away |
| NC State | defeated | Clemson | 24-17 | Home |
| Memphis | defeated | North Texas | 45-42 | Away |
| ^6^ Georgia | defeated | Florida | 43-20 | Away |
| Minnesota | defeated | Michigan State | 27-12 | Home |
| ^9^ Oregon | defeated | ^12^ Utah |
35-6 | Away |
| Miami (OH) | defeated | Ohio | 30-16 | Away |
| UT San Antonio | defeated | East Carolina | 41-27 | Home |
| ^19^ Louisville | defeated | ^21^ Duke |
23-0 | Home |
| Miami | defeated | Virginia | 29-26 | Home |
| ^7^ Texas | defeated | BYU | 35-6 | Home |
| Auburn | defeated | Mississippi State | 27-13 | Home |
| Appalachian State | defeated | Southern Mississippi | 48-38 | Home |
| ^14^ Notre Dame | defeated | Pittsburgh | 58-7 | Home |
| Nebraska | defeated | Purdue | 31-14 | Home |
| Iowa State | defeated | Baylor | 30-18 | Away |
| Tulane | defeated | Rice | 30-28 | Away |
| ^23^ USC | defeated | California | 50-49 | Away |
| Louisiana | defeated | South Alabama | 33-20 | Away |
| Arkansas State | defeated | Louisiana Monroe | 34-24 | Away |
| Boise State | defeated | Wyoming | 32-7 | Home |
| Coastal Carolina | defeated | Marshall | 34-6 | Home |
| ^24^ Tennessee | defeated | Kentucky | 33-27 | Away |
| ^18^ Air Force | defeated | Colorado State | 30-13 | Away |
| ^5^ Washington | defeated | Stanford | 42-33 | Away |
| Troy | defeated | Texas State | 31-13 | Away |
| ^2^ Ohio State | defeated | Wisconsin | 24-10 | Away |
| UCLA | defeated | Colorado | 28-16 | Home |
| ^13^ Ole Miss | defeated | Vanderbilt | 33-7 | Home |
| Georgia Tech | defeated | ^17^ North Carolina |
46-42 | Home |
| Arizona State | defeated | Washington State | 38-27 | Home |
| Oklahoma State | defeated | Cincinnati | 45-13 | Home |
| ^20^ James Madison | defeated | Old Dominion | 30-27 | Home |
| Fresno State | defeated | UNLV | 31-24 | Home |
| Nevada | defeated | New Mexico | 34-24 | Home |
| Arizona | defeated | ^11^ Oregon State |
27-24 | Home |
| San José State | defeated | Hawai'i | 35-0 | Away |