Have you experimented with another launcher like Bottles or even Steam?
You could eliminate the possibility that it is a Lutris settings problem that way.
but choose inherit from the environment. Try to only post the errors in the log (usually at the end) because it will be long.
Also the only time I've ever seen that error is when a person's drivers are not up to date or they don't have the latest vkd3d / Wine installed.
You should also have the correct dependencies - VC 2019 Redist
In the runner debug options for the game ( here) choose "Inherit from the environment" and upload the log to something like pastebin.
Native, binary