abcdqfr

All positions of power are aloft piles of blood and gold. We had someone real up there, for a time. At least on paper. What else can we do? Burn it all down from within? 🙊

Follow the cash. Find the Fasc. (see also Epstein flight logs)

Looks like San Fran! Damned societal double standards

You're gonna put your knee out jerking it like that

That is on fact the point I was making, thank you for reaching it. There are multiple causes for excess urination and craving water, not necessarily sugar related. The takeaway is that both conditions should be considered... Or like, go to the doctor..?

Actually not quite, just looked up DI.... Feel free to double fact check me on this:

`Below is a detailed fact‐check showing why diabetes insipidus (DI) is unrelated to blood sugar, and how it differs fundamentally from diabetes mellitus (DM).

Summary of Key Findings

Diabetes insipidus is a disorder of water balance caused by problems with antidiuretic hormone (ADH) production or response, leading to excessive urination and thirst; it has nothing to do with blood glucose regulation citeturn0search1turn0search6. In contrast, diabetes mellitus is a group of conditions characterized by insulin insufficiency or resistance, causing elevated blood sugar levels citeturn0search2turn0search3. Both share the Greek root “diabetes” (“to pass through”) because of polyuria, but are otherwise distinct diseases citeturn0search5turn0search7.

What Is Diabetes Insipidus?

Definition and Epidemiology

• DI is a rare disorder in which the kidneys cannot concentrate urine, producing up to 20 L/day of dilute urine instead of the normal 1–3 L/day citeturn0search1turn0search6.
• Prevalence is roughly 1 in 25,000 people worldwide citeturn0search11.

Mechanism: ADH Dysregulation

• Central DI: Insufficient ADH (vasopressin) production by the hypothalamus/pituitary citeturn0search0turn0search1.
• Nephrogenic DI: Renal tubules fail to respond to ADH citeturn0search5.
• Without ADH signaling, water reabsorption in the collecting ducts is impaired, so water is lost in urine.

Clinical Features

• Polyuria: Excessive urine volume, often > 10 L/day citeturn0search1turn0search6.
• Polydipsia: Intense thirst and preference for cold water citeturn0search1turn0search7.
• Risk of dehydration if fluid intake doesn’t match losses.

Diagnosis & Treatment

• Diagnosis: Water-deprivation test, measurement of ADH levels, and pituitary imaging (MRI) for central DI citeturn0search0turn0search1.
• Treatment:
  • Central DI: Desmopressin (synthetic ADH) citeturn0search0turn0search1.
  • Nephrogenic DI: Low-salt diet, thiazide diuretics, NSAIDs to reduce urine output citeturn0search1turn0search5.

What Is Diabetes Mellitus?

Definition and Epidemiology

• DM refers to disorders of glucose metabolism characterized by hyperglycemia (fasting plasma glucose ≥ 126 mg/dL or A1C ≥ 6.5 %) citeturn0search2turn0search14.
• Over 38 million Americans (~ 1 in 10) and hundreds of millions worldwide are affected citeturn0search3turn0search8.

Mechanism: Insulin and Glucose

• Type 1 DM: Autoimmune destruction of pancreatic β-cells → absolute insulin deficiency.
• Type 2 DM: Insulin resistance and relative insulin deficiency citeturn0search4turn0search12.
• Leads to impaired cellular glucose uptake and elevated blood sugar.

Clinical Features

• Polyuria & Polydipsia: Osmotic diuresis from glucose-rich urine citeturn0search2turn0search3.
• Polyphagia: Increased hunger.
• Long-term: Cardiovascular disease, neuropathy, retinopathy.

Diagnosis & Treatment

• Diagnosis: Fasting plasma glucose, oral glucose tolerance test, A1C measurement citeturn0search14.
• Treatment:
  • Lifestyle: Diet, exercise, weight loss.
  • Medications: Insulin for type 1; metformin, SGLT2 inhibitors, GLP-1 agonists for type 2 citeturn0search4turn0search18.

Why the Confusion?

• Both conditions cause frequent urination and thirst, hence share the name “diabetes” from the Greek for “siphon” citeturn0search5turn0search15.
• The key distinction is water vs. sugar regulation—DI involves ADH and free water clearance; DM involves insulin and glucose metabolism citeturn0search7turn0search2.

Bottom line: DI is not related to sugar intake or insulin. Cutting down on sugar will not affect DI. It’s a water‐balance disorder entirely separate from diabetes mellitus.`

DOGE?

"A little Chernobyl over here, a little over there... I can do it for less!" -some long dead cunt

It's easy to die in your sleep. Just find a nice cold section of sidewalk to curl up on and let the wind chill sap your life away. Just don't go to work!

Wait, you guys aren't constantly repairing things out of sheer financial incentive? ... Got any change?