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Reddit is making sitewide protests basically impossible
(www.theverge.com)
This is a most excellent place for technology news and articles.
Lack of imagination.
Mods can still dump 10k trash messages in a sub making it unusable. (Or smart messages in the case of most subreddit who are trash anyway).
Set-up automoderator with rules reventing anyone below 5 billions karma to participate.
Ban everyone.
I'm sure there are a lot of other options.
They'd get banned for spam.