I haven't used one, but my guess would be they're fine if you're a "web browsing and email" sort, but most of us here probably aren't, and then you're going to have pain when you need to install some tool that expects to be installed globally, because so many pieces of open source software assume the "spew files all over /usr
" installation method.
Feels like you'd be spending a lot of time fighting expectations in the same way that Nix has to.