GraphHopper
I can't speak for your particular interests, but in my experience there is something for pretty much every niche. That's what keeps YouTube in their dominant position as well.
Proton can also be used by other tools like Bottles. It's very similar to Lutris but with a more general purpose focus, rather than just gaming.
The health related reasons others gave are interesting, but my reasoning is this pretty simple: On normal weekdays I don't really have breakfast, so brushing my teeth as one if the first things makes sense. On weekends I like to have breakfast with my family so I'd like to get rid of morning breath before I talk to people.
That's the thing. I get that people using the service on a third party client and not seeing ads is hurting their bottom line as they use bandwidth and not make money. But just banning them outright is a shit move. Ideally they would've made it part of Reddit Premium to make that a bit more worthwhile.