this post was submitted on 11 Jan 2025
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[–] [email protected] 12 points 2 months ago (7 children)

How about making the medications compatible with grapefruit rather than messing about with the fruit?

[–] [email protected] 41 points 2 months ago* (last edited 2 months ago) (2 children)

Grapefruits are already man-made hybrids of others fruits. Hybridizing fruit is way less complex and way more safe than tweaking medication and trying to get it approved.

[–] [email protected] 12 points 2 months ago

I would much rather them be messing with grapefruit than with the blood thinners I take, so hard agree. Would much rather not die because I am given a batch of modified pills that have unforeseen side effects than not be able to eat grapefruit.

[–] [email protected] 1 points 2 months ago

They're hybrids, surprisingly though, they're not man-made, or not directly. People introduced oranges and pomelos to Barbados. But the plants then crossbread of their own will in the wild, creating grapefruits :)

I do agree it's easier to tweak the fruit.

[–] [email protected] 26 points 2 months ago (3 children)

It's a grapefruit x mandarin hybrid. We've been cross-breeding species for, well, ever. Some foods you're familiar with may be hybrids and you don't even realize it

[–] [email protected] 10 points 2 months ago

The lemon is a hybrid of the bitter orange and citron.

[–] [email protected] 8 points 2 months ago

life didn't give us lemons, we made them ourselves

[–] [email protected] 1 points 2 months ago (1 children)
[–] [email protected] 1 points 2 months ago (1 children)
[–] [email protected] 3 points 2 months ago (1 children)

Apples are different. Apple seeds from a particular tree will grow some other kind of apple. The seeds are genetically different from the parent tree, and most of them are not tasty. The ones that turn out to be tasty are grown into new plants from cuttings.

[–] [email protected] 2 points 2 months ago

So apples and oranges.

[–] [email protected] 23 points 2 months ago (1 children)

Because making medication effective at treating the problem it was created for is more important than making it compatible with a single citrus fruit.

[–] [email protected] 11 points 2 months ago

Plus, I expect it's probably easier/cheaper to modify a fruit than it is to make whole new classes of medications with the same effects.

[–] [email protected] 16 points 2 months ago

Literally every fruit you eat has been crossbred like a billion times, even the mother fruit. Chill out.

[–] [email protected] 15 points 2 months ago

Grapefruit interacts with specific metabolic pathways in the liver. Most medications are broken down by the liver. That's just how the body works, unfortunately

[–] [email protected] 13 points 2 months ago (2 children)

messing about with the fruit

You make it sound as though they’re meth addicts feverishly trying to breed a grapefruit with a lionfish and a carburetor lol

[–] [email protected] 9 points 2 months ago

I would watch that 1960s horror film.

[–] [email protected] 2 points 2 months ago (1 children)

I have two of those. Don't test me.

[–] [email protected] 1 points 2 months ago

Don’t test me.

you'd piss hot.

[–] [email protected] 1 points 2 months ago (1 children)
[–] [email protected] 1 points 2 months ago

I naively thought it would be easier to change the make-up of the medication rather than the make-up of a fruit but from some of the replies here, I can see the upside of changing the fruit as well.