Ever seen a down syndrome n16g3r baby? They look like boogers.
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Official confirmation that Reddit liberals have arrived.
I'll comment about the inevitable result of neoliberalism all day but I think we both know that loser doesn't count as a liberal by any standard.
How many generations of inbreeding would be necessary before it returns again?
Down syndrome is a result of errors in DNA replication during the formation of gametes or early development. While there are genetic risk factors they're not particularly linked to inbreeding.
By far the largest risk factor is the age of the parents.
Seems like very basic research - I wonder how far in the future it might turn into a human treatment, and what improvements people would see?
I genuinely wonder where the line is between curing defects and eugenics. It seems razor thin how it can swing easiy into dark territory.
I remember this was literally the question posed to us by an ethics professor 20 years ago. Now it's a reality.
A person with Down's can live a happy fulfilling life, but most parents would never choose to have a child with Down's if it could be born 'normal' instead. So we're essentially removing them from the gene pool and human race.
It's eugenics for sure. I'm not sure if it's unethical though. It's pretty complex.
The one thing you can guarantee of the human race though is we will do it before we really put the thought in to "if" we should do it.
I have ADHD and have 2 boys on the spectrum. Despite the challenges with my younger and higher needs son I don't know if given the opportunity to play God if I would. As you said it's an extremely complex question I don't know if anyone is truly equipped to answer and I'd argue we definitely aren't mature enough to start playing God.
Here be dragons.
we're essentially removing them from the gene pool
I don't think Downs works like that.
It's already being removed, since people choose abortion over downs and since people with Downs don't have children (normally).
It is not hereditary. It's an error or mutation that can occur for anyone. The chances are higher the older the parents are.
There's hereditary factors but it's because the genes in charge of replication are flawed.
My understanding is that women with down syndrome only have a 30-50% chance of fertility, and men are generally infertile. Additionally there are laws in place to prevent those with mental disabilities from being taken advantage of sexually, which lessens the chance of children even more. It's a spontaneous mutation, so they wouldn't be removed from the gene pool.
If 99℅ of pregnancies are screened and the gene's edited then, yeah, you're effectively eliminating people with Down's from our world.
Unless society collapses and the Quirk returns naturally.
Reminds me of Cyprus with Thalassemia,
they were mostly against termination, but when they introduced screenings, and optional termination. the disease mysteriously disappeared. even though publicly they were against it
(it's a story I read about it a long time ago, so take it with a grain of sand)
This isn't eugenics or close to it, it's fixing actual problems before someone is born, not choosing who has rights to breed. If they announced a therapy to guarantee a child will grow up immune to corporate propaganda or be able to use their brain in a rational, well-planned and thoughtful way, and have exceptional language skills, we should voluntarily hand the world over to them. Because what's happening right now is the opposite of that.
Right now capitalism is imposing eugenics on us. The system and the cost of life has created a very real system deciding who can have families. If tools emerged that could guarantee the kids we DO have aren't subject to the same weaknesses and limitations, we need to capitalize on every advantage we can.
Yeah this is scary. Down syndrome is definitely in the gray area too where it can be viewed negatively but plenty of people have it and lead fulfilling lives. Wipe cystic fibrosis out of a fetus and all but the most staunch biological purists would agree it was a good thing. Make your fetus white, blonde, and blue eyed and it's obviously eugenics. I don't know how I feel about this.
Completely apart from the ethics, I think this technology is really cool though.
They live fulfilling lives at the detriment of others who have to live less fulfilling lives, maybe they don't see it that way, but its added responsibility
Actual Nazi rhetoric btw
There are a lot of reports and interviews with ppl who have down syndrome that are not happy at all with their situation. Ie. Unable to have a driving licence, go to university, huge disadvantage on the dating market… the list goes on. I’m not saying they can’t have fulfilling moments but we also shouldn’t kid ourselves and look at down syndrome with rosy eyes. If it could be cured everyone would do it instantly.
https://en.m.wikipedia.org/wiki/Social_model_of_disability
Notice how everything you listed is a result of society's treatment of them and not necessarily their learning disability itself?
Phenotype vs biological normative.
Deaf people will decry “fixing” a person hearing impaired in the womb. Yet, it’s a correction to biological normative.
Adjusting a gender to a different one in the womb would not be.
Adjusting physical traits for looks wouldn’t be.
Adjusting a physical trait like spinal deformity would be.
Adjusting for general height would not be.
If there is something diagnosable in the ICD-10 codes we have, and it’s preventable in a population, it would not be eugenetics. Remove gene editing as the tool, but just say “magic” a cure. Cures apply to diseases, not traits.
You don’t cure being black. You CAN cure sickle cell.
I think the line is pretty clear.
You simply use existing diagnostic criteria of deviation from biological normative function.
The diagnostic criteria and the culture that determines that criteria are both subject to change. lots of things that people consider perfectly normal now would be classified as a disease or disorder in the past.
Who defines the diagnostic criteria?
Gattaca is the semi-dystopian vision of our future if we just walk blindly down this path without legislating it properly in advance.
For those who haven't seen the movie: Rich people start paying for perfect "designer babies". A person's genetic information becomes their whole identity; businesses only hire employees with the most genetic predisposition towards being good at the job, while regular people conceived "the old-fashioned way" get McJobs. Even wearing glasses is treated like a crippling disability that immediately and visibly marks someone as "inferior".
It is extremely important that we pass laws to ensure that genetic engineering doesn't create a new caste system.
Isn't eugenics more about choosing who can reproduce for the best outcome? Curing after the facts doesn't seem to fit that.
I think what is talking about is like everyone now forced to have blue eyes with gene editing so is it considered a type of soft genocide or something.
Nah, man, forget blue eyes. Think neon purple. With natural blue hair. Fucking anime shit.
And just imagine what furries will do to themselves once they get their paws on this tech...
Batman beyond. They will create batman beyond.
Nono, the paws come after
Yeah now you're talking! Cat girls/boys here we come!
Blade runner or deus ex timeline
it considered a type of soft genocide
Not saying this is what you're saying, but it's attitudes like this that make me see red. We gotta stop letting our society become so atomized that we've replaced tribalism with Turbo Tribalism.
they should poll people with down syndrome. not carers, not family, no people who work with them.
if they consider they idea obscene, them or should be considered obscene, of they consider it a must, then it's ok.