It's getting hot in here : science

[–] [email protected] 57 points 11 months ago (1 children)

Immune response isn't controlled by the brain tho.

[–] [email protected] 35 points 11 months ago (4 children)

I'm pretty sure there's a shiny bead in your brain that regulates your temperature. Keep in mind, all my knowledge on this subject comes from Osmosis Jones.

[–] [email protected] 11 points 11 months ago (1 children)

AFAIK (undergrad biology), immune cells release signal molecules that cause temperature increase, more or less localized and wholly independent from the nervous system.

[–] [email protected] 9 points 11 months ago* (last edited 11 months ago)

The reason you experience the chills when you spike a fever is the brain sets the desired temperature higher and as a result you perceive cold at your current body temperature. And also why you feel like you are in a sauna when your fever breaks, because the inverse is true.

To be clear this set point does mean induction of peripheral actions to actually elevate the temperature, but the central component of this symphony is the hypothalamus.

There is a lot of uncertainty around fever signaling, here is a great summary of what we know.

[–] [email protected] 4 points 11 months ago

I concur!

[–] [email protected] 4 points 11 months ago

You like this chain, Jones?

[–] [email protected] 2 points 11 months ago* (last edited 11 months ago)

~~Closest thing I can think of is~~ https://en.wikipedia.org/wiki/Brainstem.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6034117/

~~The body may act intelligently.. But not directly most related to the brain.~~

Edit: https://en.m.wikipedia.org/wiki/Fever#Pathophysiology_of_fever_induction

[–] [email protected] 54 points 11 months ago

I actually think your brain is the first thing to succumb to fever damage, no? Still, quality cartoon.

[–] [email protected] 43 points 11 months ago* (last edited 11 months ago) (1 children)

Still alive, evildoer? Get ready for my CYTOKINE STORM

[–] [email protected] 22 points 11 months ago (1 children)

But Sir, those are banned by a body-wide treaty!

[–] [email protected] 34 points 11 months ago

I AM THE BODY

[–] [email protected] 31 points 11 months ago

But brain will be takin the most damage and have no control on it whatsoever .

[+] [email protected] 26 points 11 months ago (4 children)

[removed by mod]

[–] [email protected] 38 points 11 months ago

You're basically describing an allergic reaction.

[–] [email protected] 14 points 11 months ago

There are many, many diseases caused by your own immune system attacking your body. The brain itself cannot "attack" anything unless you count seizures and the like. Maybe several forms of psychosis could fit the bill with even more stretching, but there is little your brain can do outside of interfering with bodily functions. If you seizure that hard outside of a hospital bed, you're probably SOL in most cases.

[–] [email protected] 12 points 11 months ago (1 children)

Lupus has entered the chat

[–] [email protected] 2 points 11 months ago

It's never House.

[–] [email protected] 5 points 11 months ago

Great description of Ebola.

[–] [email protected] 10 points 11 months ago

I'm gonna live or die tryin'

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